Crystal structure of
the carboxyl domain
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264 residues (nt 7647-8438), 29354 dalton
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10 20 30 40 50
0 MNRGFFNMLG RRPFPAPTAM WRPRRRRQAA PMPARNGLAS QIQQLTTAVS
50 ALVIGQATRP QPPRPRPPPR QKKQAPKQPP KPKKPKTQEK KKKQPAKPKP
100 GKRQRMALKL EADRLFDVKN EDGDVIGHAL AMEGKVMKPL HVKGTIDHPV
150 LSKLKFTKSS AYDMEFAQLP VNMRSEAFTY TSEHPEGFYN WHHGAVQYSG
200 GRFTIPRGVG GRGDSGRPIM DNSGRVVAIV LGGADEGTRT ALSVVTWNSK
250 GKTIKTTPEG TEEW
Ala 22 (8.3 %) Asx 0 (0.0 %) Cys 0 (0.0 %) Asp 9 ( 3.4 %) Glu 12 (4.5 %) Phe 9 (3.4 %) Gly 24 (9.1 %) His 6 (2.3 %) Ile 8 ( 3.0 %) Lys 25 (9.5 %) Leu 14 (5.3 %) Met 10 (3.8 %) Asn 8 (3.0 %) Pro 28 (10.6 %) Gln 14 (5.3 %) Arg 23 (8.7 %) Ser 12 (4.5 %) Thr 17 (6.4 %) Val 15 ( 5.7 %) Trp 4 (1.5 %) Tyr 4 (1.5 %) Glx 0 (0.0 %) xxx 0 (0.0 %)
(-) (+) net pH Cys Asp Glu Tyr COOH charge His Lys Arg NH2 charge charge |
1.0 0.00 8.99 11.99 4.00 1.00 -.02 6.00 25.00 23.00 1.00 55.00 54.98 |
1.5 0.00 8.97 11.98 4.00 0.99 -.06 6.00 25.00 23.00 1.00 55.00 54.94 |
2.0 0.00 8.89 11.93 4.00 0.97 -.21 6.00 25.00 23.00 1.00 55.00 54.79 |
2.5 0.00 8.66 11.79 4.00 0.92 -.63 6.00 25.00 23.00 1.00 55.00 54.37 |
3.0 0.00 8.01 11.36 4.00 0.78 -1.85 6.00 25.00 23.00 1.00 55.00 53.15 |
3.5 0.00 6.48 10.19 4.00 0.53 -4.80 5.99 25.00 23.00 1.00 54.99 50.19 |
4.0 0.00 4.04 7.68 4.00 0.27 -10.01 5.98 25.00 23.00 1.00 54.98 44.97 |
4.5 0.00 1.84 4.32 4.00 0.10 -15.74 5.94 25.00 23.00 1.00 54.94 39.20 |
5.0 0.00 0.68 1.81 4.00 0.04 -19.47 5.82 25.00 23.00 1.00 54.82 35.35 |
5.5 0.00 0.23 0.64 4.00 0.01 -21.12 5.45 25.00 23.00 1.00 54.45 33.33 |
6.0 0.00 0.07 0.21 4.00 0.00 -21.72 4.56 25.00 23.00 1.00 53.56 31.84 |
6.5 0.00 0.02 0.07 4.00 0.00 -21.91 3.00 25.00 23.00 0.99 51.99 30.08 |
7.0 0.00 0.01 0.02 4.00 0.00 -21.97 1.44 25.00 23.00 0.97 50.41 28.44 |
7.5 0.00 0.00 0.01 4.00 0.00 -21.99 0.55 24.99 23.00 0.92 49.46 27.47 |
8.0 0.00 0.00 0.00 4.00 0.00 -22.00 0.18 24.96 23.00 0.78 48.92 26.92 |
8.5 0.00 0.00 0.00 3.99 0.00 -22.01 0.06 24.87 23.00 0.53 48.46 26.45 |
9.0 0.00 0.00 0.00 3.96 0.00 -22.04 0.02 24.60 22.99 0.27 47.88 25.84 |
9.5 0.00 0.00 0.00 3.86 0.00 -22.14 0.01 23.78 22.98 0.10 46.87 24.73 |
10.0 0.00 0.00 0.00 3.60 0.00 -22.40 0.00 21.51 22.93 0.04 44.48 22.08 |
10.5 0.00 0.00 0.00 2.95 0.00 -23.05 0.00 16.52 22.77 0.01 39.30 16.25 |
11.0 0.00 0.00 0.00 1.89 0.00 -24.11 0.00 9.53 22.30 0.00 31.83 7.72 |
11.5 0.00 0.00 0.00 0.88 0.00 -25.12 0.00 4.08 20.91 0.00 24.99 -0.13 |
12.0 0.00 0.00 0.00 0.33 0.00 -25.67 0.00 1.45 17.47 0.00 18.92 -6.75 |
12.5 0.00 0.00 0.00 0.11 0.00 -25.89 0.00 0.48 11.50 0.00 11.98 -13.91 |
13.0 0.00 0.00 0.00 0.04 0.00 -25.96 0.00 0.15 5.53 0.00 5.68 -20.28 |
(-) (+) net
pI Cys Asp Glu Tyr COOH charge His Lys Arg NH2 charge charge
11.49 0.00 0.00 0.00 0.89 0.00 -25.11 0.00 4.16 20.95 0.00 25.11 0.00
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