Department of Molecular Microbiology, Washington University in St. Louis, School of Medicine

 (photo)

Milton J. Schlesinger

Professor
Phone, office: (314)-362-2762
Phone, lab: (314)-362-2761
FAX: (314)-362-1232
email: schlesin_m@borcim.wustl.edu

527 McDonnell Science Building
Box 8230 Department of Molecular Microbiology
Washington University School of Medicine
660 South Euclid Avenue
St. Louis, MO 63110-1093.

Research Interests | CV | Publications |

Research Interests

My research program is focussed on the assembly of enveloped animal viruses. We are using molecular genetics (site-directed mutagenesis, complementation, revertant analysis via PCR) to analyze the events required for budding of newly replicated viruses from infected tissue-culture cells.
Our model system employs Sindbis virus, a non-pathogenic RNA enveloped virus whose genome can be manipulated via a cDNA clone and subsequent transfection with transcribed RNA.

keywords:RNA virus, membrane, site-mutagenesis, budding, virus assembly

CV

Date of birth: November 26, 1927

Education
1951B.S. Physics, Yale University, New Haven, Connecticut
1953M.S. Biophysics, Rochester University, Rochester, New York
1959Ph.D. Biochemistry, University of Michigan, Ann Arbor, Michigan

Professional Experience and Appointments
Present PositionProfessor
Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri
1953-1956Research Associate
University of Michigan, Ann Arbor, Michigan
1959-1960Research Associate, N.I.H. Postdoctoral Fellow
University of Michigan, Ann Arbor, Michigan
1960-1961Guest Research Investigator, N.S.F. Postdoctoral Fellow
Istituto Superiore di Sanita, Rome, Italy
1961-1964 Research Associate
Massachusetts Inst. of Technology, Department of Biology, Boston, Massachusetts
1964-1967Assistant Professor
Washington University School of Medicine, St. Louis, Missouri
1967-1972Associate Professor
Washington University School of Medicine, St. Louis, Missouri
1973-1975
1987-1989		Acting Chairman
Department of Microbiology, Washington University School of Medicine, St. Louis, Missouri
1974-1975Visiting Scientist
Imperial Cancer Research Fund Laboratories, London, England
1977-1985Associate Director, Center for Basic Cancer Research
Washington University School of Medicine, St. Louis, Missouri
1989-1990Visiting Scholar
Department of Biochemistry and Molecular Biology, Harvard University, Cambridge, Mass

Honors
1951Phi Betta Kappa; Sigma Xi (Yale)
1951-1953Atomic Energy Commission Fellowship
1956-1958University Teaching Fellowship, University of Michigan
1958-1959 Rackham Predoctoral Fellowship, University of Michigan
1959-1960National Institutes of Health Postdoctoral Fellowship
1960-1961National Science Foundation Postdoctoral Fellowship
1990-1992Sigma Xi National Lecturer

Professional Activities
1975-1978Member - Physiological Chemistry Research Study Committee, American Heart Association
1978-1982Member- National Science Foundation Advisory Panels
Panel 1 - Human Biology Section
Panel 1 - Biochemistry Section
1982-1987Member - Editorial Board, Journal of Biological Chemistry
1975-1991Associate Editor, Virology
1975-1992 Honorary Editorial Board, International Journal of Biochemistry
1983-1993Member - Editorial Board, Molecular and Cell Biolgoy
1988-1991Member - Scientific Advisory Board, Friedrich Miescher-Institut, Germany
1991-Present Chairman-Scientific Advisory Board, Friedrich Miescher-Institut, Germany

Professional Society Memberships
American Society of Biological Chemists
American Association for the Advancement ofScience
American Society of Microbiologists
American Society for Virologists
American Chemical Society
The Protein Society

Publications

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WWW
Department of Molecular Microbiology, Box 8230
Washington University School of Medicine
St. Louis, MO 63110-1093 USA

Tel 314-362-7250, FAX 314-362-1232