Doering lab publications on C. neoformans

J. Stacey Klutts, Steven B. Levery, and Tamara L. Doering. A beta-1,2-xylosyltransferase from Cryptococcus neoformans defines a new family of glycosyltransferases. In press, J. Biol. Chem., 2007 [PDF]
Tricia R. Cottrell, Cara L. Griffith, Hong Liu, Ashley A. Nenninger, andTamara L. Doering. The pathogenic fungus Cryptococcus neoformans expresses two functional GDP-mannose transporters with distinct expression patterns and roles in capsule synthesis. In press, Eukaryotic Cell, 2007. [PDF] Cover image. [Cover]
Amy J. Reese, Aki Yoneda, Julia A. Breger, Anne Beauvais, Hong Liu, Cara L. Griffith, Indrani Bose, Myoung-Ju Kim, Colleen Skau, Sarah Yang, Julianne Sefko, Masako Osumi, Jean-Paul Latge, Eleftherios Mylonakis, and Tamara L. Doering. Loss of cell wall alpha(1-3) glucan affects Cryptococcus neoformans from ultrastructure to virulence. Molecular Microbiology, 63, 1385-1398, 2007. [PDF]Cover image. [Cover PDF]
Aki Yoneda and Tamara L. Doering. A eukaryotic capsular polysaccharide is synthesized intracellularly and secreted via exocytosis. Molecular Biology of the Cell, 17, 5131-5140, 2006.[PDF]
J. Stacey Klutts, Aki Yoneda, Morgann Reilly, Indrani Bose, and Tamara L. Doering. Glycosyltransferases and their products: Cryptococcal variations on fungal themes. FEMS Yeast Research, 6, 499-512, 2006. [PDF[
Stephen M. Beverley, Katherine L. Owens, Melissa Showalter, Cara L. Griffith, Tamara L. Doering, Victoria C. Jones, and Michael R. McNeil. Idenitfication of eukaryotic UDP-galactopyranose mutase in microbial and metazoal pathogens. Eukaryotic Cell, 4, 1147-1154, 2005. [PDF]
Brendan Loftus et al. The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science, 307, 1321-1324, 2005.[PDF] [supplementary material]
Cara Griffith, J. Stacey Klutts, Lijuan Zhang, Steven B. Leverey, and Tamara L. Doering. UDP-glucose dehydrogenase plays multiple roles in the biology of the pathogenic fungus Cryptococcus neoformans. J. Biol. Chem. 279, 51669-51676, 2004. [PDF]
Aaron Tenney, Randall Brown, Charles Vasquez, Jennifer K. Lodge, Tamara L. Doering, and Michael R. Brent. Predicting genes in the genome sequence of Cryptococcus neoformans, a fungal pathogen with numerous extremely short introns. Genome Research, 14, 2330-2335, 2004. [PDF]   
Isabelle Mouyna, Christine Henry, Tamara L. Doering, and Jean-Paul Latge. Gene silencing with RNA interference in the human pathogenic fungus Aspergillus fumigatus. FEMS Microbiol. 237, 317-324, 2004. [PDF]

Jeramia J. Ory, Cara L. Griffith, and Tamara L. Doering. Copper regulation of gene transcription in Cryptococcus neoformans. Yeast, 21, 919-926, 2004. [PDF]

Maor Bar-Peled, Cara L. Griffith, Jeramia J. Ory, and Tamara L. Doering. Biosynthesis of UDP-GlcA, a key metabolite for capsular polysaccharide synthesis in the pathogenic fungus Cryptococcus neoformans. Biochemical J., 381, 131-136, 2004. [PDF]
Amy J. Reese and Tamara L. Doering. Cell wall alpha-1,3-glucan is required to anchor the Cryptococcus neoformans capsule. Molecular Microbiology, 50, 1401-1409, 2003. [PDF]
Ulf Sommer, Hong Liu, and Tamara L. Doering. An alpha-1,3-mannosyl transferase of Cryptococcus neoformans. J. Biol. Chem., 278, 47724-47730, 2003. [PDF]
Tricia R. Cottrell and Tamara L. Doering. Silence of the strands: RNA interference in eukaryotic pathogens. Trends in Microbiology, 11, 37-43, 2003. [PDF]
Indrani Bose, Amy J. Reese, Jeramia J. Ory, Guilhem Janbon, and Tamara L. Doering. A yeast under cover: The capsule of Cryptococcus neoformans. Eukaryotic Cell, 2, 655-663, 2003. [PDF]

Maor Bar-Peled, Cara L. Griffith, and Tamara L. Doering. Functional cloning and characterization of a UDP-glucuronic acid decarboxylase: The pathogenic fungus Cryptococcus neoformans elucidates UDP-xylose synthesis. Proc. Natl. Acad. Sci. USA, 98, 12003-12008, 2001. [PDF]

Hong Liu, Tricia R. Cottrell, Lynda M. Pierini, William E. Goldman, and Tamara L. Doering. RNA interference in the pathogenic fungus Cryptococcus neoformans. Genetics, 160, 463-470, 2001. [PDF]
Lynda Pierini and Tamara L. Doering. Spatial and temporal sequence of capsule construction in Cryptococcus neoformans. Molecular Microbiology, 141, 105-115, 2001. [PDF]

Tamara L. Doering. How does Cryptococcus get its coat? Trends in Microbiology, 8, 545-551, 2000. [Response to a comment on this article Trends in Microbiology 9, p. 113 (2001).] [PDF]
Tamara L. Doering. A unique alpha-1,3 mannosyl transferase of the pathogenic fungus Cryptococcus neoformans. J. Bacteriol., 181, 5482-5488, 1999. [PDF]
Sarah P. Franzot and Tamara L. Doering. Specificity of GPI inositol acylation in Cryptococcus neoformans. Biochem. J., 340, 25-32, 1999. [PDF]
Lin-Chi Chen, David L. Goldman, Tamara L. Doering, Liise-anne Pirofski, and Arturo Casadevall. The antibody response to Cryptococcus neoformans proteins in rodents and humans. Infection & Immunity, 67, 2218-2224, 1999.
Tamara L. Doering, Joshua D. Nosanchuk, Wendy K. Roberts and Arturo Casadevall. Melanin interactions with protein: A potential cryptococcal defense against microbicidal proteins. Medical Mycology, 37, 175-182, 1999.

Non-crypto publications by Tamara L. Doering

Primary data papers
David A. Bernlohr, Tamara L. Doering, Thomas J. Kelly, Jr. and M. Daniel Lane. Tissue specific expression of p422 protein, a putative lipid carrier in mouse adipocytes. Biochem. Biophys. Res. Comm. 132, 850-855, 1985.
David W. Saffen, Kathleen A. Presper, Tamara L. Doering and Saul Roseman. Molecular cloning and structural analysis of the E. coli ptsH, ptsI, and crr genes. J. Biol. Chem. 262, 16241-16253, 1987.
James D. Bangs, Tamara L. Doering, Paul T. Englund and Gerald W. Hart. Biosynthesis of a variant surface glycoprotein of Trypanosoma brucei: Processing of the glycolipid membrane anchor and N-linked oligosaccharides. J. Biol. Chem. 263, 17697-17705, 1988.
Wayne J. Masterson, Tamara L. Doering, Gerald W. Hart and Paul T. Englund. A novel pathway for glycan assembly: Biosynthesis of the glycosyl-phosphatidylinositol membrane anchor of the trypanosome variant surface glycoprotein. Cell 56, 793-800, 1989.
Tamara L. Doering, Wayne J. Masterson, Paul T. Englund, and Gerald W. Hart. Biosynthesis of the glycosyl phosphatidylinositol membrane anchor of the trypanosome variant surface glycoprotein: Origin of the non-acetylated glucosamine. J. Biol. Chem. 264, 11168-11173, 1989.
Jessica L. Krakow, Tamara L. Doering, Wayne J. Masterson, Gerald W. Hart and Paul T. Englund. A glycolipid from Trypanosoma brucei related to the variant surface glycoprotein membrane anchor. Mol. Biochem. Parasitol. 36, 263-270, 1989.
Mark F. Bean, James D. Bangs, Tamara L. Doering, Paul T. Englund, Gerald W. Hart, Catherine Fenselau, and Robert J. Cotter. Assessing heterogeneity of the high-mannose glycopeptide gp432 on the variant surface glycoprotein of trypanosomes: A comparison of plasma desorption mass spectrometry and radiolabeling techniques. Anal. Chem., 61, 2686-2688, 1989.
Wayne J. Masterson, Jayne Raper, Tamara L. Doering, Gerald W. Hart, and Paul T. Englund. Fatty acid remodeling: A novel reaction sequence in the biosynthesis of trypanosome glycosyl phosphatidylinositol membrane anchors. Cell, 62, 73-80, 1990.
Tamara L. Doering, Jayne Raper, Laurence U. Buxbaum, Jeffrey I. Gordon, Steven P. Adams, Gerald W. Hart, and Paul T. Englund. An analog of myristic acid with selective toxicity for African trypanosomes. Science, 252, 1851-1854, 1991.
Tamara L. Doering, Melissa S. Pessin, Eleanor F. Hoff, Gerald W. Hart, Dan M. Raben, and Paul T. Englund. Trypanosome metabolism of myristate, the fatty acid required for the variant surface glycoprotein membrane anchor. J. Biol. Chem. 268, 9215-9222, 1993.
Tamara L. Doering, Melissa S. Pessin, Gerald W. Hart, Daniel M. Raben, and Paul T. Englund. The fatty acids in unremodeled trypanosome phosphatidylinositols. Biochem. J., 299, 741-746, 1994.
Tamara L. Doering, Tianbao Lu, Karl A. Werbovetz, George Gokel, Gerald W. Hart, Jeffrey I. Gordon, and Paul T. Englund. The toxicity of myristic acid analogs towards African trypanosomes. Proc. Natl. Acad. Sci. USA, 91, 9735-9739, 1994.
Tamara L. Doering and Randy Schekman. GPI-anchor attachment is required for Gas1p transport from the endoplasmic reticulum in COP II vesicles. EMBO J., 15, 182-191, 1996.
Christine Sütterlin, Tamara L. Doering, Frauke Schimmöller, Stephan Schröder and Howard Riezman. Specific requirements for the ER to Golgi transport of GPI-anchored proteins in yeast. J. Cell Science, 111, 2703-2714, 1997.
Tamara L. Doering and Randy Schekman. GPI anchor attachment in a yeast in vitro system. Biochem. J., 328, 669-675, 1997.
Reviews and Methods
Paul T. Englund, Jessica L. Krakow, Dale Hereld, Tamara L. Doering, Wayne J. Masterson and Gerald W. Hart. Biosynthesis of the trypanosome variant surface glycoprotein: Attachment of the glycolipid membrane anchor. In: Molecular Basis of the Action of Drugs and Toxic Substances (N. Castognoli, T.P. Singer and C.C. Wang, eds.) Walter de Gruyter, New York, 1987.
Dale Hereld, Jessica L. Krakow, Tamara L. Doering, Wayne J. Masterson, Gerald W. Hart, and Paul T. Englund. The membrane-anchoring glycolipid of the trypanosome variant surface glycoprotein. In: Post-Translational Modification of Proteins by Lipids (U. Brodbeck and C. Bordier, eds.) Springer-Verlag, Berlin, 1987.
Paul T. Englund, Dale Hereld, Jessica L. Krakow, Tamara L. Doering, Wayne J. Masterson and Gerald W. Hart. The glycolipid anchor of the trypanosome variant surface glycoprotein: Its biosynthesis and cleavage. In: The Biology of Parasitism (P. Englund and A. Sher, eds.), Alan R. Liss, Inc., New York, 1988.
Tamara L. Doering, Wayne J. Masterson, Gerald W. Hart, and Paul T. Englund. Biosynthesis of glycosyl phosphatidylinositol membrane anchors. J. Biol. Chem., 265, 611-614, 1990.
Tamara L. Doering, Jayne Raper, Laurence U. Buxbaum, Gerald W. Hart, and Paul T. Englund. Biosynthesis of glycosyl phosphatidylinositol protein anchors. Methods: A Companion to Methods in Enzymology, 1, 288-296, 1990.
Kojo Mensa-Wilmot, Tamara L. b, Jayne Raper, Laurence U. Buxbaum, Gerald W. Hart, and Paul T. Englund. Glycosyl phosphatidylinositol membrane anchors in African trypanosomes. In: Molecular and Immunological Aspects of Parasitism (C.C. Wang, ed.), AAAS Press, Washington, D. C., 1991.
Tamara L. Doering. Glycosyl phosphatidylinositol protein anchors of African trypanosomes: Biosynthesis and therapeutic implications. Ph.D. dissertation, Johns Hopkins University, 1991.
Jayne Raper, Tamara L. Doering, Lawrence U. Buxbaum, and Paul T. Englund. Glycosyl phosphatidylinositols in Trypanosoma brucei. Experimental Parasitology 76, 216-220, 1993.
Tamara L. Doering, Paul T. Englund, and Gerald W. Hart. Detection of glycophospholipid protein anchors on proteins. In: Current Protocols in Molecular Biology, F. A. Ausubel et al, Eds., Unit 17, Analysis of Glycoconjugates, Guest Eds. A. Varki and J. Coligan, Greene Publishing and Wiley-Interscience, NY. 1993.
Tamara L. Doering. Glycosylphosphoinositol linkages of membrane glycoproteins. In: Cell Surface and Extracellular Glycoconjugates: Structure and Function (David D. Roberts and Robert P. Mecham, eds.), Academic Press, Inc., Orlando, Fla. 1993.
Randy Schekman, Charles Barlowe, Sebastian Bednarak, Joe Campbell, Tamara Doering, Rainer Duden, Meta Kuehn, Michael Rexach, Tom Yeung, and Lelio Orci. Coat Proteins and selective protein packaging into transport vesicles. Cold Spring Harbor Symposium on Quantitative Biology, 60, 11-21, 1995.